Satellite Software Adapted for Alzheimer's Brain Scans
The same software used to analyze satellite images has been adapted to look for signs of Alzheimer's in MRI scans.
Credit: ESA

Satellite pictures of Earth and images of the human brain have at least one thing in common: To be useful to scientists, both require sophisticated software to make sense of a mountain of tiny details.

Researchers say tools originally designed to analyze image data from space have been adapted to search for signs of Alzheimer's disease in the brain.

"If you have a space image and you have to select part of an image — a field or crops — you need special routines to extract the information," Carlos Fernández de la Peña, of the Spanish tech company Elecnor Deimos, explained in a statement. "Is this pixel a field, or a road?"

Fernández de la Peña and colleagues worked on software for the European Space Agency's (ESA) now-defunct Envisat satellite that could process raw image data to identify specific elements on the ground. The Earth-observing spacecraft was launched in 2002 and ended its mission in 2012, but its processing software lives on. [Earth From Space: Envisat Satellite Photos]

Envisat’s Advanced Synthetic Aperture Radar (ASAR) captured this image on April 8, 2012 at 11:09 GMT. The image was transmitted in X-band to the Santa Maria station in the Azores, Portugal, operated by Edisoft. It shows Spain’s Canary Islands. It is the last Envisat data transmitted via X-band before the communication anomaly.
Envisat’s Advanced Synthetic Aperture Radar (ASAR) captured this image on April 8, 2012 at 11:09 GMT. The image was transmitted in X-band to the Santa Maria station in the Azores, Portugal, operated by Edisoft. It shows Spain’s Canary Islands. It is the last Envisat data transmitted via X-band before the communication anomaly.
Credit: ESA/Edisoft

ESA officials say computer scientists at Elecnor Deimos adapted Envisat's tools to help create a new program called AlzTools 3D Slicer for analyzing brain scans of people who may have Alzheimer's disease.

"Looking at and analyzing satellite images can be compared to what medical doctors have to do to understand scans like MRIs (Magnetic Resonance Images)," Fernández de la Peña said. "They also need to identify features indicating malfunctions according to specific characteristics."

There is currently no known cause, cure or even effective prevention strategy for the brain-wasting Alzheimer's disease. But researchers have been looking for better ways to detect changes in the brain associated with the condition, such as the buildup of the protein amyloid-beta, nerve cell damage and brain shrinkage.

AlzTools is now being used by medical researchers at the University of Castilla La Mancha in Albacete in Spain, according to ESA officials. Instead of interpreting topographic details, the program scrutinizes brain regions like the hippocampus, where atrophy is associated with Alzheimer's.

From memory foam to ultraviolet-blocking sunglasses, technologies developed for space often find their way back down to Earth as spinoffs. Advanced digital image processing was developed by NASA in the 1960s to get a better look at the moon, but those techniques eventually helped enable body-imaging techniques, such as CATScans and MRI.

Richard Seddon, who represents Spain as a technology broker for ESA, said AlzTools could be another example of such innovation.

"Even if being developed for specific applications, we often see that space technologies turn out to provide innovative and intelligent solutions to problems in non-space sectors, such as this one," Seddon said in a statement.

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