Biosphere 2, located about 20 miles north of Tucson, Arizona, that was sealed in 1991 with 8 scientists inside who were trying thrive in an environment that simulated 7 Earth ecosystems. The biospherians ran into many problems, including a lack of oxygen, which cut their two-year mission short. Columbia University now maintains the facility and conducts research at the site. CREDIT: Columbia University.

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